Information
Minion the Dizzy
Frameshift
Legacy Name: Frameshift
The Custom Common Experiment #404
Owner: Tashamon
Age: 8 years, 7 months, 4 weeks
Born: September 1st, 2015
Adopted: 8 years, 7 months, 4 weeks ago
Adopted: September 1st, 2015
Statistics
- Level: 1
- Strength: 10
- Defense: 10
- Speed: 11
- Health: 10
- HP: 10/10
- Intelligence: 0
- Books Read: 0
- Food Eaten: 0
- Job: Unemployed
Because of this relationship, if a nucleotide in the DNA strand is inserted or deleted, it can completely change the structure of the protein produced - often to disastrous effect. Insertions and deletions of bases in numbers non-divisible by three are known as frameshift mutations. This is because they change the reading frame, resulting in every codon after the mutation being changed. The earlier in the sequence that these changes occur, the greater the change to the resultant protein there will be, resulting in a radically altered and possibly non-functional protein.
Diseases caused by these types of mutations currently have no cure. However the use of modified viruses to insert working copies of a gene into affected cells, or gene therapy, is currently being developed as a treatment and in the future it may even be possible to fix the malfunctioning genes entirely.